General Information
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Product
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Cytokeratin 20 Antibody BIOTIN-Conjugated
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Description
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BIOTIN-Conjugated keratin, type I cytoskeletal 20 Antibody N-epitope
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey, Mouse
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Immunogen
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Synthetic peptide taken within amino acid region 300-350 human keratin, type I cytoskeletal 20 protein.
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Accession #
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NCBI: NP_061883.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.75 µg/µl in antibody stabilization buffer
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Form
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BIOTIN-Conjugated
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Clonality
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Polyclonal
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Determinant
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N-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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P35900
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Overview
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Plays a role in maintaining keratin filament organization in intestinal epithelia. When phosphorlyated it is involved in the secretion of mucin in the small intestine.
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Molecular Function
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Structural constituent of cytoskeleton; Apoptosis
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Subcellular Location
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Cytoplasm
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Expression
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Mainly expressed in the itenstinal epithelium, expressed in luminal cells of colonic mucosa. Also expressed in Merkel cells of keratinzed oral mucosa.
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Structure
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Heterotetramer of two type I and two type II keratins, associates with KRT8.
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Alternative Nomenclature
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CD20 antibody
CK20 antibody
Cytokeratin20 antibody
K20 antibody
Keratin 20 antibody
keratin 21, rat, homolog of antibody
Keratin antibody
Keratin type I cytoskeletal 20 antibody
KRT20 antibody
KRT21 antibody
Protein IT antibody
type I cytoskeletal 20 antibody
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