General Information |
|
Product |
SFRP5 Antibody FITC |
Description |
FITC-Conjugated Secreted frizzled-related protein 5 Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 150-200 on SFRP5 |
Accession # |
GenBank: AAD25052.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.67 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunohistochemistry | 1:50-1:150 |
Immunoprecipitation | 1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina. |
Molecular Function |
PDZ domain binding, Wnt-protein binding, Wnt-activated receptor activity |
Subcellular Location |
Secreted |
Expression |
Highly expressed in the retinal pigment epithelium (RPE) and pancreas. Weak expression in heart, liver and muscle. |
Alternative Nomenclature |
Frizzled related protein 1b FRP 1b SARP3 Secreted apoptosis related protein 3 Secreted frizzled related protein 5 |
Protein information supplied by UniProt
Fabgennix SFRP5 Antibody has been used in 1 Publication |
|
Zeng, Min, et al. "TFAP2C inhibits cell autophagy to alleviate myocardial ischemia/reperfusion injury by regulating miR‐23a‐5p/SFRP5/Wnt5a axis." The FASEB Journal 37.6 (2023)
|
1:500 dilution |
Publishing research using SFRP5-501AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
---|---|---|---|---|
|
SFRP5-501AP | |||
|
P-SFRP5 | |||
|
SFRP5-BIOTIN | |||
|
PC-SFRP5 | |||
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(c) FabGennix International Inc.