General Information
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Product
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SHISA9 Antibody FITC-Conjugated
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Description
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FITC-Conjugated Cytosine-knot AMPA receptor modulating protein 44a Antibody
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Verified Applications
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ELISA, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey, Mouse
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Immunogen
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Synthetic peptide taken within amino acid region 250-300 on CKAMP44a protein.
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Accession #
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NCBI: ADD64956.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.64-0.72 µg/µl in antibody stabilization buffer
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9CZN4
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Overview
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Regulates short term neuronal synaptic plasticity in dentate gyrus. Also associates with AMPA receptosr in synaptic spines, promotes AMPA receptor desensitization at excitatory synapses.
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Molecular Function
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Regulation of short-term neuronal synaptic plasticity
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Subcellular Location
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Cell projection; Single-pass type I membrane protein; Cell junction; Synapse
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Expression
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Brain specific, expressed mostly in neurons and most brain structures during embryonic and postnatal development.
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Structure
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Component of some AMPA receptors complex, and atleast composed of some AMPA receloptr, CACNG2, SHISA9 and also a low level of DLG5
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Alternative Nomenclature
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CKAMP44 antibody
shisa family member 9 antibody
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