General Information |
|
Product |
PD-L1 Antibody FITC |
Description |
FITC-Conjugated Programmed cell death 1 ligand 1 Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Monkey Predicted: Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid reigon 80-130 on human Progammed cell death 1 ligand 1 protein. |
Accession # |
NCBI: NP_054862 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
FITC-Conjugated |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:10,000 |
Immunohistochemistry | 1:50-1:100 |
Immunoprecipitation |
1:150 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production. |
Molecular Function |
Receptor |
Subcellular Location |
Isoform 1 : Cell membrane; Single-pass type I membrane protein Isoform 2 : Endomembrane system; Single-pass type I membrane protein |
Expression |
Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes. |
Structure |
Belongs to the immunoglobulin superfamily. BTN/MOG family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
Alternative Nomenclature |
B7 H antibody B7 homolog 1 antibody CD 274 antibody PD L1 antibody PDCD1 ligand 1 antibody PDCD1L1 antibody PDCD1LG1 antibody PDL 1 antibody Programmed death ligand 1 antibody RGD1566211 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
PDL1-101AP | |||
|
PDL1-BIOTIN | |||
|
P-PDL1 | |||
|
PC-PDL1 | |||
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