General Information
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Product
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DNA PKcs Blocking Peptide
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Description
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Antigenic Blocking Peptide DNA-dependent protein kinase catalytic subunit Antibody
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid region 4000-4128 of human DNPK1 protein.
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20°C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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P78527
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Overview
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Receptor for netrin required for axon guidance; may trigger signaling for axon repulsion; acts as a dependence receptor required for apoptosis induction; tumor suppressor gene.
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Molecular Function
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netrin receptor activity; transcription coactivator activity; transmembrane signaling receptor activity; Developmental protein
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Subcellular Location
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axon; cytosol; plasma membrane
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Expression
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Found in axons of the central and peripheral nervous system; differentiated cell types of the intestine
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Structure
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Belongs to the immunoglobulin superfamily. DCC family; Contains 6 fibronectin type-III domains; Contains 4 Ig-like C2-type (immunoglobulin-like) domains
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Alternative Nomenclature
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DNA dependent protein kinase catalytic subunit antibody
DNA PK catalytic subunit antibody
DNA-PKcs antibody
DNAPK antibody
DNAPK catalytic subunit antibody
DNPK 1 antibody
Hyper radiosensitivity of murine scid mutation, complementing 1 antibody
HYRC 1 antibody
p350 antibody
p460 antibody
PKRDC antibody
Protein Kinase DNA Activated Catalytic Polypeptide antibody
XRCC 7 antibody
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