General Information
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Product
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Src Antibody FITC-Conjugated
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Description
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FITC-Conjugated Proto-oncogene tyrosine-protein kinase Src Antibody C-epitope
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Verified Applications
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CM, ELISA, IF, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 400-500 on human Src protein.
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Accession #
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NCBI: NP_005408.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.56-0.60 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Determinant
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C-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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Immunocytochemistry
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1:100
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Immunofluorescence
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1:100
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Immunohistochemistry
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1:100
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Immunoprecipitation
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1:250
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Western Blot
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1:500
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Protein
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Uniprot #
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P12931
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Overview
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Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis migration, and transformation.
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Molecular Function
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ATP binding, ephrin receptor binding, heme binding, ion channel binding, enzyme binding, growth factor receptor binding, integrin binding, kinase activity
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Subcellular Location
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Cell membrane, mitochondrion inner membrane, nucleus, cytoplasm (Note: Localizes to focal adhesion sites following integrin engagement. Localization to focal adhesion sites requires myristoylation and SH3 domain.)
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Expression
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Expressed ubiquitously. Platelets, neurons and osteoclasts express 5-fold to 200-fold higher levels than most other tissues.
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Structure
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Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
Contains 1 protein kinase domain.
Contains 1 SH2 domain.
Contains 1 SH3 domain.
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Alternative Nomenclature
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ASV antibody
Avian sarcoma virus antibody
c SRC antibody
CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA antibody
cSrc antibody
EC 2.7.10.2 antibody
Neuronal CSRC tyrosine specific protein kinase antibody
Neuronal SRC antibody
Oncogene SRC antibody
p60 Src antibody
Proto oncogene tyrosine protein kinase Src antibody
Protooncogene SRC antibody
protooncogene SRC Rous sarcoma antibody
Src antibody
SRC Oncogene antibody
SRC proto oncogene non receptor tyrosine kinase antibody
SRC1 antibody
Tyrosine kinase pp60c src antibody
Tyrosine protein kinase SRC 1 antibody
v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog antibody
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