General Information
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Product
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CGRP Antibody BIOTIN
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Description
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BIOTIN-Conjugated Calcitonin gene-related peptide 1 Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Mouse, Rat
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Immunogen
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Synthetic peptide corresponding to amino acids within region 350-410 mouse Calcitonin gene-related peptide 1.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5-1.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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BIOTIN-Conjugated
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Purification Method
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Immobilized antigen affinity chromatography
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Clonality
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Polyclonal
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Storage
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-20?C for long term storage
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Application Protocol
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ELISA
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1:50,000
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Immunoprecipitation
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1:200
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Western Blot
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1:500-1:5,000
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Protein
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Uniprot #
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Q99JA0
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Overview
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CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP (By similarity).`
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Molecular Function
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calcitonin receptor binding
hormone activity
signaling receptor binding
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Subcellular Location
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Secreted
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Expression
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Detected in nerve cells of cerebrum, hippocampus and pons/midbrain in newborns, and only in nerve cells of pons/midbrain in adult.
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Structure
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Belongs to the calcitonin family.
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Alternative Nomenclature
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Calcitonin/calcitonin related polypeptide alpha antibody
Alpha type CGRP antibody
Beta type CGRP antibody
CALC1 antibody
CALC2 antibody
CALCA antibody
CALCB antibody
Calcitonin 1 antibody
Calcitonin 2 antibody
Calcitonin gene related peptide I antibody
Calcitonin gene related peptide II antibody
Calcitonin related polypeptide alpha antibody
Calcitonin related polypeptide beta antibody
CGRP antibody
CGRP1 antibody
CGRP2 antibody
CT antibody
Katacalcin antibody
KC antibody
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