General Information
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Product
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TRPM8 Peptide
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Description
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Antigenic Blocking Peptide Transient receptor potential cation channel subfamily M member 8 Antibody
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Verified Applications
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Immunocompeition, Immunodepletion
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Peptide Description
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Synthetic Peptide
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Accession #
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NCBI: NP_599198.2
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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1Refer to competition assay protocol
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Protein
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Uniprot #
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Q8R455
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Overview
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Involved in detection of sensations such as coolness, activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH
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Molecular Function
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Calcium channel activity
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Subcellular Location
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cell membrane, multi-pass membrane protein, membrane raft. (Note: Localizes to membrane rafts but is also loated in the cell membrane outside of these regions where channel response to cold is enhanced compared to membrane rafts)
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Expression
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Expressed in dorsal root and trigeminal ganglia. Specifically expressed in a subset of sensory neurons, including cold-sensitive neurons in trigeminal neurons.
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Alternative Nomenclature
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Long transient receptor potential channel 6 antibody
LTrpC6 antibody
Short form of the TRPM8 cationic channel antibody
Transient receptor potential cation channel subfamily M member 8 antibody
Transient receptor potential p8 antibody
TRPP8 antibody
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