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General Information
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Product
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Lin28 Antibody
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Description
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Affinity Purified LIN28 protein Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid sequence 1-60 on Lin28A sequence.
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Accession #
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GenBank: AAH28566.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.88-0.95 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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| ELISA |
1:10,000 |
| Immunohistochemistry |
1:50-1:150 |
| Immunoprecipitation |
1:200 |
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9H9Z2
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Overview
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Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Association with translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing mRNA's
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Molecular Function
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DNA binding, mRNA binding, zinc ion binding, miRNA binding, RNA binding
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Subcellular Location
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Cytoplasm, nucleus, nucleolus. (Note: nucleolar localization observed in 10-15% of nuclei in differentiated byotubes. Shuttles between cytoplasm and nucleus. Localizes to cytoplasmic processing bodies and stress granules)
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Expression
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Expressed in embryonic stem cells (ES cells), placenta and testis.
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Alternative Nomenclature
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AL024421 antibody
CSDD1 antibody
FLJ12457 antibody
Lin 28 antibody
Protein lin-28 homolog A antibody
RNA binding protein lin 28 antibody
Tex17 antibody
ZCCHC1 antibody
Zinc finger CCHC domain containing 1 antibody
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Lin28 Antibody FITC
Lin28 Antibody BIOTIN
Lin28 Blocking Peptide
Lin28 Positive Control
