Ephrin Receptor A6 Positive Control

General Information

Product

Eprhin Receptor A6 Antibody Western Blot Positive Control

Description

Western Blot Positive Control Ephrin type-A receptor 6 isoform A Antibody

Verified Applications

WB

Immunogen

Purified Protein

Accession #

NCBI:  NP_001073917

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

B3KS12

Overview

Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).

Molecular Function

ATP-binding, Nucleotide-binding

Subcellular Location

Membrane; Single-pass type I membrane protein

Expression

Expressed in brain and testis.

Structure

Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses (By similarity).

Alternative Nomenclature

Ehk 2 antibody

EPH homology kinase 2 antibody

Eph Receptor A6 antibody

ephrin receptor EphA6 antibody

Hek12 antibody