General Information

Product

VPS26 Antibody

Description

Affinity Purified Vacuolar protein sorting-associated protein 26A Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acids 315-375 on human VPS26 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.56 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

O75436

Overview

Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3.

Molecular Function

protein transporter activity

Subcellular Location

cytoplasm, endosome membrane, preipheral membrane protein (Note: Localizes to tubular profiles adjacent to endosomes. Predominantly found in early not late endosomes)

Expression

Down-regulated in Alzheimer disease. No polymorphism or variant is however associated with Alzheimer disease for VPS26A.

Alternative Nomenclature

FLJ12930 antibody

FLJ12930 antibody

HB 58 antibody

Hbeta 58 antibody

Hbeta 58 homolog antibody

MGC94168 antibody

PEP 8A antibody

Vacuolar protein sorting 26 A antibody

Vacuolar protein sorting 26 homolog A yeast antibody

Vacuolar protein sorting associated protein 26A antibody

Vesicle protein sorting 26A antibody

VPS 26 antibody

VPS 26A antibody

General Information

Product

SEC23 Antibody

Description

Affinity Purified Protein transfer protein Sec23A Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Drosophila melanogaster, Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 700-765 on human SEC23A protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:350

Western Blot

1:500

Protein

Uniprot #

Q15436

Overview

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.

Molecular Function

ER to Golgi vesicle-mediated transport; Intracellular protein transport; Zinc ion binding

Subcellular Location

COPII vesicle coat; Cytoplasm; Endoplasmic Reticulum Membrane; Golgi Apparatus Membrane; Peripheral Membrane Protein

Structure

COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1. Interacts with SEC23IP. Interacts with HTR4. Interacts with SLC6A4. Interacts with SEC16A.

Alternative Nomenclature

CLSD antibody

Protein transport protein Sec23A antibody

SEC23-related protein A antibody

General Information

Product

SEC24A Antibody

Description

Affinity Purified Protein transport protein Sec24A Antibody

Verified Applications

CM, ELISA, ICC/IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 810-850 on SEC24A protein.

Accession #

NCBI:  NP_001099250.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.61-0.64 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

D3ZZA8

Molecular Function

Zinc ion bonding

Alternative Nomenclature

protein transport protein Sec24A antibody

SEC24 related gene family member A antibody

SEC24 related protein A antibody

SEC24 S cerevisiae related gene family member A antibody

General Information

Product

SEC24B Antibody

Description

Affinity Purified Protein transport protein Sec24B Antibody

Verified Applications

CM, ELISA, ICC, IHC, IF, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 390-430 on Sec24B protein.

Accession #

NCBI:  NP_001099944.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.59 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

D3ZW15

Molecular Function

Zinc ion bonding

Alternative Nomenclature

Protein transport protein Sec24B antibody

SC24B_HUMAN antibody

SEC24 family, member B (S. cerevisiae) antibody

SEC24 related gene family, member B antibody

SEC24-related protein B antibody

secretory protein 24 antibody

General Information

Product

SEC24C Antibody

Description

Affinity Purified Protein transport protein Sec24C Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 950-1000 on rat SEC24C protein.

Accession #

NCBI:  NP_001102926.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.59 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

B5DEG8

Molecular Function

Zinc ion bonding

Alternative Nomenclature

Protein transport protein Sec24C antibody

SC24C antibody

SC24C_HUMAN antibody

Sec 24C antibody

SEC24 related gene family, member C (S. cerevisiae) antibody

SEC24 related protein C antibody

General Information

Product

SEC24D Antibody

Description

Affinity Purified Sec24d protein Antibody

Verified Applications

CM, ELISA, ICC, IHC, IF, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Predicted:  Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 860-920 on human SEC24D protein.

Accession #

NCBI:  NP_055637

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.59 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

Dot Blot

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

O94855

Molecular Function

Zinc ion bonding

Alternative Nomenclature

KIAA0755 antibody

Protein transport protein Sec24D antibody

SEC24 family member D antibody

SEC24 related gene family, member D antibody

SEC24-related protein D antibody

General Information

Product

ORP150 Antibody

Description

Affinity Purified Hypoxia up regulated 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Rat

Immunogen

Synthetic peptide taken within amino acid region 950-999 on human Hypoxia up regulated 1.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9Y4L1

Overview

Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding.

Molecular Function

ATP binding; chaperone binding

Subcellular Location

Endoplasmic reticulum lumen

Expression

Highly expressed in tissues that contain well-developed endoplasmic reticulum and synthesize large amounts of secretory proteins. Highly expressed in liver and pancreas and lower expression in brain and kidney. Also expressed in macrophages within aortic atherosclerotic plaques, and in breast cancers.

Structure

Part of a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX. Belongs to the heat shock protein 70 family.

Alternative Nomenclature

150 kDa oxygen regulated protein antibody

170 kDa glucose regulated protein antibody

DKFZp686N08236 antibody

FLJ94899 antibody

FLJ97572 antibody

glucose regulated protein 170 antibody

Grp 170 antibody

Grp170 antibody

HSP 12A antibody

HSP12A antibody

Hyou1 antibody

Hypoxia up regulated 1 antibody

Orp 150 antibody

Orp150 antibody

oxygen regulated protein (150kD) antibody

General Information

Product

EHD2 Antibody

Description

Affinity Purified EH domain-containing protein 2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse Rat

Immunogen

Synthetic peptide taken within amino acid 420-450 on human EH-Domain Containing Protein 2.

Accession #

NCBI:  NP_055416.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9NZN4

Overview

Plays a role in membrane reorganization in response to nucleotide hydrolysis

Molecular Function

ATP binding; GTPase activity; nucleic acid binding; calcium ion binding; GTP binding

Subcellular Location

Cell membrane, Endosome, Membrane

Expression

Highly expressed in heart and moderately expressed in placenta, lung, and skeletal muscle.

Structure

Homodimer and homooligomer. Interacts with EHD1 and MYOF. May also interact with EHD3 and EHD4.

Alternative Nomenclature

EH domain containing 2 antibody

EH domain containing 3 antibody

EHD 2 antibody

EHD3 antibody

FLJ96617 antibody

PAST 2 antibody

General Information

Product

EHD3 Antibody

Description

Affinity Purified EH domain-containing protein 3 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse Rat

Immunogen

Synthetic peptide taken within amino acid region 475-535 on human EH-domain containing protein 3.

Accession #

NCBI:  NP_055416.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.58 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9NZN3

Overview

Plays a role in endocytic transport

Molecular Function

ATP binding;GTPase activity;nucleic acid binding;calcium ion binding;GTP binding

Subcellular Location

Cell membrane, Cytoplasm, Endosome, Membrane

Expression

Highly expressed in heart and brain and moderately expressed in kidney, liver, and placenta.

Structure

Homooligomer, and heterooligomer with EHD1, EHD2 and EHD4

Alternative Nomenclature

EH domain containing 3 antibody

EHD2 antibody

EHD3 antibody

PAST3 antibody

General Information

Product

EHD4 Antibody

Description

Affinity Purified EH domain-containing protein 4 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse Rat

Immunogen

Synthetic peptide taken within amino acid region 420-450 on EH-domain containing 4 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9H223

Overview

Plays a role in early endosomal transport

Molecular Function

ATP binding;GTPase activity;nucleic acid binding;calcium ion binding;GTP binding

Subcellular Location

Cell membrane, Endosome, Membrane

Expression

Highly expressed in pancreas and heart.

Structure

Homooligomer, and heterooligomer with EHD1, EHD2 and EHD3

Alternative Nomenclature

EH domain containing 4 antibody

Hepatocellular carcinoma associated protein 10/11 antibody

HCA11 antibody

HGNC:3245 antibody

Ortholog of rat pincher antibody

PAST4 antibody