Phospho-PDE10A Blocking Peptide

Product no.: P-PPD10A

General Information
Product	Phospho-PDE10A Peptide
Description	Antigenic Blocking Peptide Phosphorylated Phosphodiesterase 10A Antibody
Verified Applications	Immunodepletion, Immunocompetition
Peptide Description	Phosphorylated synthetic MAP common to all PDE10A variants. Taken within amino acid region 1-50 on human PDE10A protein.
Accession #	GenBank: AAD32596.1
Physical Properties
Quantity	250 µg
Volume	100 µl
Form	Antigenic Blocking Peptide
Storage	-20⁰C for long term storage
Application Protocol
Competition/Depletion assay	Refer to competition assay protocol
Protein
Uniprot #	Q9Y233
Overview	Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.
Molecular Function	Hydrolase, metal-ion binding, cGMP binding
Subcellular Location	Cytoplasm
Expression	Abundant in the putamen and caudate nucleus regions of brain and testis, moderately expressed in the thyroid gland, pituitary gland, thalamus and cerebellum.
Structure	Homodimer
Alternative Nomenclature	5''-cyclic phosphodiesterase 10A antibody cAMP and cAMP inhibited cGMP 3'5' cyclic phosphodiesterase 10A antibody cAMP and cAMP-inhibited cGMP 3'' antibody FLJ11894 antibody HSPDE10A antibody PDE 10A antibody Pde10a antibody Phosphodiesterase 10A antibody

Protein information supplied by UniProt