General Information
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Product
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PINK1 Antibody FITC
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Description
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FITC-Conjugated Serine/Threonine-protein kinase PINK1 Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse
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Immunogen
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Synthetic peptide corresponding to unique amino acid sequence on human PINK1 protein.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.75 µg/µl in antibody stabilization buffer
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunohistochemistry |
1:50-1:150 |
Immunoprecipitation |
1:200 |
Western Blot
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1:500
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Protein
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Uniprot #
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Q9BXM7
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Overview
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During cellular stress it serves to protect against mitochondrial dysfunction through the phosphorylation of mitochondrial proteins. Uses selective autophagy to clear mitochondria that has been damaged.
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Molecular Function
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Kinase, Serine/threonine-protein kinase, Transferase
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Subcellular Location
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Mitochondrion outer membrane; Single-pass membrane protein, Cytoplasm
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Expression
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Expression is detected at high levels in the heart, skeletal muscles and testis. Expression is detected at lower levels in the brain, placenta, liver, kidney, pancreas, prostate, ovary and small intestine.
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Structure
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Interacts with PARK2 and FBXO7
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Alternative Nomenclature
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BRPK antibody
FLJ27236 antibody
mitochondrial antibody
PARK 6 antibody
Phosphatase and Tensin Homolog antibody
PINK 1 antibody
Protein kinase BRPK antibody
PTEN induced putative kinase 1 antibody
Serine/threonine-protein kinase PINK1 antibody
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