General Information

Product

SLC9A3 Antibody

Description

Affinity Purified Sodium/hydrogen exchanger 3 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to amino acids within region 590-640 on human SLC9A3 protein.

Physical Properties

Quantity

100 ug

Concentration

0.5-1.5 ﾵg/ﾵl in antibody stabilization buffer

Immunoglobulin

IgG

Conjugate

Unconjugated

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20ﾡC for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:50-1:100

Immunofluorescence

1:50-1:100

Immunohistochemistry

1:50-1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P48764

Molecular Function

PDZ domain binding

potassium:proton antiporter activity

sodium:proton antiporter activity

Subcellular Location

Plasma membrane

Alternative Nomenclature

MGC126718 antibody

Na(+)/H(+) exchanger 3 antibody

NHE 3 antibody

SLC9A 3 antibody

Sodium / Hydrogen Exchanger 3 antibody

Sodium/hydrogen exchanger, apical epithelial antibody

Solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 antibody

Solute carrier family 9 (sodium/hydrogen exchanger), member 3 antibody

Solute carrier family 9 member 3 antibody

General Information

Product

BMP1 Antibody

Description

Affinity Purified Bone morphogenetic protein 1 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 680-730 on human BMP1 protein.

Accession #

NCBI:  NP_001190

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50-0.56 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:2,000

ELISA

1:2,000

Western Blot

1:500

Protein

Uniprot #

P13497

Overview

Cleaves the C-terminal propeptides of procollagen I, II and II. Induces bone and cartilage formation.

Molecular Function

Chondrogenesis; Differentiation; Osteogenesis; Calcium, Zinc, Metal binding

Subcellular Location

trans-Golgie network; secreted; ECM

Expression

Ubiquitous

Structure

Belongs to peptidase M12A family. Contains 5 CUB domains and 2 EGF-like domains.

Alternative Nomenclature

Mammalian tolloid protein antibody

mTld antibody

OI13 antibody

PCOLC antibody

PCP2 antibody

Procollagen C endopeptidase antibody

TLD antibody

Tolloid, Drosophila, homolog of antibody

General Information

Product

Bestrophin 3 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Monkey

Immunogen

Accession #

NCBI: NP_116124.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500-1:1,000

Protein

Uniprot #

Q8N1M1

Overview

Forms calcium-sensitive chloride channels. Permeable to bicarbonate.

Molecular Function

Ion transport; Calcium, Chloride.

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Expression

Skeletal muscle and weakly in brain, spinal cord, bone marrow and retina.

Structure

Belongs to bestrophin Family

Alternative Nomenclature

BEST 3 antibody

Bestrophin3 antibody

MGC13168 antibody

MGC40411 antibody

Vitelliform macular dystrophy 2-like protein 3 antibody

VMD2L3 antibody

General Information

Product

PNPLA3 Antibody

Description

Affinity Purified Patatin-like phospholipase domain-containing protein 3 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 150-200 on human Patatin-like phospholipase domain-containing protein 3.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:4,000

ELISA

1:4,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q9NST1

Overview

Multifunctional enzyme which has both triacylglycerol lipase and acylglycerol O-acyltransferase activities.

Molecular Function

Phospholipase A2 Activity; Lipid degradation and metabolism; Acyltransferase; Hydrolase; Transferase

Subcellular Location

Membrane; Single-pass type II membrane protein

Expression

By changes in energy balance: down-regulated following very low-calorie diet, whereas refeeding elevates the mRNA level.

Structure

Contains 1 patatin domain

Alternative Nomenclature

Acylglycerol O acyltransferase antibody

Adiponutrin antibody

ADPN antibody

C22orf20 antibody

Calcium independent phospholipase A2 epsilon antibody

IPLA2-epsilon antibody

Patatin like phospholipase domain containing 3 antibody

patatin like phospholipase domain containing protein 3 antibody

phospholipase A2, calcium independent, epsilon antibody

General Information

Product

MC4 Receptor Antibody

Description

Affinity Purified Melanocortin receptor 4 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 10-60 on human MC4R protein.

Accession #

NCBI:  NP_005903.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P32245

Overview

Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).

Molecular Function

Melanocortin receptor activity, melanocyte-stimulating hormone receptor activity, neuropeptide binding, ubiquitin protein ligase binding

Subcellular Location

cell membrane, multi-pass membrane protein, membrane raft. (Note: Localizes to membrane rafts but is also loated in the cell membrane outside of these regions where channel response to cold is enhanced compared to membrane rafts).

Expression

Brain, placental, and gut tissues.

Alternative Nomenclature

MC4 R antibody

Melanocortin receptor 4 antibody

MGC126851 antibody

MGC138197 antibody

General Information

Product

ACTH Antibody

Description

Affinity Purified Adrenocorticotropin Hormone Antibody

Verified Applications

ELISA, IHC-Fr, IHC-P, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Predicted: Chicken, Chimpanzee, Cow, Dog, Goat, Guinea pig, Macaque Monkey, Orangutan, Sheep

Immunogen

Synthetic peptide corresponding to ACTH aa 138-176. 

Sequence:

SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF

Accession #

NCBI:  AAX36901

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.67-0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:250

Immunocytochemistry

1:250

Immunofluorescence

1:200

Immunohistochemistry

1:250

Immunoprecipitation

1:200

Western Blot

1:1000 Predicted Molecular weight: 29 kDa

Protein

Uniprot #

UPI00004EBE53

Overview

Stimulates adrenal glands and release cortisol.

Molecular Function

GPCR; Hormone activity

Subcellular Location

Secreted

Expression

ACTH and MSH are produced by the pituitary gland

Structure

Belongs to POMC family

Alternative Nomenclature

Alpha Melanocyte Stimulating Hormone antibody

Beta Endorphin antibody

Beta Lipotropin antibody

Beta Melanocyte Stimulating Hormone antibody

Beta-endorphin antibody

CLIP antibody

Corticotropin Like Intermediary Peptide antibody

Met-enkephalin antibody

MSH antibody

NPP antibody

Opiomelanocortin prepropeptide antibody

POC antibody

POMC antibody

Tetracosactide antibody

General Information

Product

Adenylate Cyclase 1 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rabbit, Rat

Immunogen

Synthetic peptide corresponding to conserved sequence at or near C terminal end of protein that is unique to rat/mouse Adenylyl Cyclase 1 protein.

Accession #

GenBank: AAC29478 

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55- 0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500. Detects a band 127-10 kDa

Protein

Uniprot #

O88444

Overview

This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina

Molecular Function

ATP-binding, Calmodulin-binding, Magnesium, Metal-binding, Nucleotide-binding

Subcellular Location

Membrane; Multi-pass membrane protein. Cytoplasm

Expression

Expressed throughout inner ear development. Brain, retina and adrenal medulla.

Structure

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Contains 2 guanylate cyclase domains

Alternative Nomenclature

3'5' cyclic AMP synthetase antibody

ADCY1 antibody

adenyl cyclase antibody

Adenylate cyclase 1 antibody

ATP pyrophosphate lyase antibody

Brain adenylate cyclase 1 antibody

Ca(2+)/calmodulin activated adenylyl cyclase antibody

EC 4.6.1.1 antibody

General Information

Product

ADCY2 Antibody

Description

Affinity Purified Particulate Adenylate cyclase type 2 Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence from rat Particulate Adenylyl Cyclase 2 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Western Blot

1:1,000

Protein

Uniprot #

P26769

Overview

Membrane-bound calmodulin-insensitive adenylyl cyclase.

Molecular Function

Adenylate cyclase activity; cAMP biosynthesis; ATP-binding; Magnesium; Metal binding; Nucleotide-binding

Subcellular Location

Membrane; Multi-pass membrane protein

Expression

Brain and in lower levels, the olfactory epithelium and lung.

Structure

Interacts with RAF1

Alternative Nomenclature

3',5' cyclic AMP synthetase antibody

Adenylate cyclase II antibody

AC2 antibody

Adenylate cyclase 2 (brain) antibody

ATP pyrophosphate lyase 2 antibody

FLJ16822 antibody

FLJ45092 antibody

HBAC2 antibody

KIAA1060 antibody

MGC133314 antibody

Type II adenylate cyclase antibody

General Information

Product

ADCY3 Antibody

Description

Particulate Adenylate cyclase type 3 Antibody Affinity Purified

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Dog, Human, Mouse, Rat

Immunogen

Synthetic peptide generated against a sequence unique to PAC3 protein. All peptides were amidated before conjugation.

Accession #

NCBI:  NP_004027

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Form

Polyclonal

Clonality

Rabbit

Determinant

Affinity Purified

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

O60266

Overview

Mediates odorant detection via modulation of intracellular cAMP concentration

Molecular Function

Adenylate cyclase activity; cAMP biosynthesis; ATP-binding; Magnesium; Metal binding; Nucleotide-binding

Subcellular Location

Membrane; Multi-pass membrane protein

Expression

Brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle

Structure

Belongs to adenylyl cyclase class-4 and guanylyl cyclase family.  Contains 2 guanylate cyclase domains.

Alternative Nomenclature

ATP pyrophosphate-lyase 3 antibody

olfactive type antibody

General Information

Product

Adenylate Cyclase 4 Antibody

Description

Affinity Purified Adenylate cyclase type 4 Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on rat Particulate Adenylyl Cyclase 4 protein.

Accession #

NCBI:  NP_062158

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.526 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:100-1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:100-1:200

Immunofluorescence

1:100-1:200

Immunohistochemistry

1:100-1:200

Western Blot

1:500

Protein

Uniprot #

Q66HK5

Molecular Function

Nucleotide-binding

Subcellular Location

Membrane

Structure

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family

Alternative Nomenclature

AC4 antibody

Adcy4 antibody

Adenylate cyclase 4 antibody

ATP pyrophosphate-lyase 4 antibody