General Information |
|
Product |
Prostaglandin E2 receptor EP3 subtype Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated Prostaglandin E2 Receptor subtype isoform 7 Antibody |
Verified Applications |
CM, ELISA, ICC, IF, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse |
Immunogen |
Synthetic peptide taken within amino acid region 300-350 on human Prostaglandin E2 receptor EP3 subtype. |
Accession # |
NCBI: NP_942010.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5-0.6 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
Confocal Microscopy |
1:250 |
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunocytochemistry |
1:250 |
Immunofluorescence |
1:250 |
Immunohistochemistry |
1:250 |
Immunoprecipitation |
1:250 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems (By similarity). |
Molecular Function |
Prostaglandin E receptor activity, G-protein coupled receptor |
Subcellular Location |
Cell membrane; Multi-pass membrane |
Expression |
Expressed in small intestine, heart, pancreas, gastric fundic mucosa, mammary artery and pulmonary vessels. |
Structure |
Belongs to the G-protein coupled receptor 1 family. |
Alternative Nomenclature |
EP 2 antibody Human prostaglandin E2 receptor antibody PGE2 receptor EP2 subtype antibody Prostaglandin E receptor 2 EP2 subtype antibody PTGER2 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-EP3.2 | |||
|
EP3-321AP | |||
|
EP3.2-FITC | |||
|
PC-EP3.2 | |||
Display accessory details |
Select your currency:
(c) FabGennix International Inc.