General Information
|
|
Product
|
TLR13 Peptide
|
Description
|
Antigenic Blocking Peptide Toll-like receptor 13 Antibody
|
Verified Applications
|
Immunocompeition, Immunodepletion
|
Peptide Description
|
Synthetic peptide taken within amino acid region 400-480 of mouse TLR13 protein.
|
Accession #
|
GenBank: AAI17914.1
|
Physical Properties
|
|
Quantity
|
250 µg
|
Volume
|
100 µl
|
Form
|
Antigenic Blocking Peptide
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
Competition/Depletion assay
|
Refer to competition assay protocol
|
Protein
|
Uniprot #
|
Q6R5N8
|
Overview
|
Component of innate and adaptive immunity that recognizes and binds 23S rRNA from bacteria. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
|
Molecular Function
|
protein homodimerization activity, rRNA binding
|
Subcellular Location
|
endosome membrane, single-pass type I membrane protein
|
Alternative Nomenclature
|
Toll like receptor 13 antibody
|
|
|