General Information |
|
Product |
AIM2 Positive Control |
Description |
Western Blot Positive Control Interferon-inducible protein AIM2 |
Verified Applications |
WB |
Immunogen |
Purified Protein |
Accession # |
NCBI: NP_004824 |
|
|
Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
|
|
Western Blot |
1:500 |
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|
Uniprot # |
|
Overview |
Innate immune response recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity. |
Molecular Function |
Apoptosis, Immunity, Inflammatory response, Innate Immunity |
Expression |
Expressed in spleen, small intestine, peripheral blood leukocytes and testis. Induced by IFNG/IFN-gamma and IFNB1/IFN-beta |
Structure |
Self-associates; forms homodimers in response to cytosolic dsDNA and the dsDNA serves as oligomerization platform |
Alternative Nomenclature |
Absent in melanoma 2 antibody PYHIN4 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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AIM2-201AP | |||
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AIM2-FITC | |||
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P-AIM2 | |||
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AIM2-BIOTIN | |||
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