General Information |
|
Product |
PDE8B Antibody FITC-Conjugated |
Description |
FITC-Conjugated Pan Phosphodiesterase 8B Antibody |
Verified Applications |
CM, ELISA, ICC, IF, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Bovine, Human, Monkey, Mouse, Rat |
Immunogen |
Synthetic cyclic peptide common to all PDE8B variants. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
Confocal Microscopy |
1:200 |
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunocytochemistry |
1:200 |
Immunofluorescence |
1:200 |
Immunohistochemistry |
1:200 |
Immunoprecipitation |
1:250 |
Western Blot |
1:500-1:2,000 |
|
|
Uniprot # | E9PXX4 |
Overview |
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in specific signaling in the thyroid gland. |
Molecular Function |
3',5'-cyclic-AMP phosphodiesterase activity, Hydrolase, Metal-binding |
Expression |
Widely expressed |
Structure |
Belongs to the cyclic nucleotide phosphodiesterase family. PDE8B subfamily. Contains 1 PER-ARNT-SIM (PAS) domain. |
Alternative Nomenclature |
3' 5' cyclic nucleotide phosphodiesterase 8B antibody Cell proliferation-inducing gene 22 protein antibody FLJ11212 antibody High affinity cAMP specific and IBMX insensitive 3' 5' cyclic phosphodiesterase 8B antibody HSPDE 8B antibody PDE8B antibody Phosphodiesterase8B antibody PIG22 antibody |
Protein information supplied by UniProt
FabGennix PDE8B Antibody has been used in 4 Publications |
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Petersen, T. S., et al. "Distribution and function of 3', 5'-Cyclic-AMP phosphodiesterases in the human ovary." Molecular and cellular endocrinology (2015). PMID25578602
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Immunohistochemistry; Human |
Shimizu-Albergine, Masami et al. “cAMP-Specific Phosphodiesterases 8A and 8B, Essential Regulators of Leydig Cell Steroidogenesis.” Molecular Pharmacology 81.4 (2012): 556–566. PMC3310417
|
Immunofluorescence, Immunoprecipitation, Western Blot; Mouse |
Sasseville, Maxime et al. “Characterization of Novel Phosphodiesterases in the Bovine Ovarian Follicle.” Biology of Reproduction 81.2 (2009): 415–425. PMC2849824
|
Western Blot; Bovine |
Baxendale, Rhona W., and Lynn R. Fraser. "Mammalian sperm phosphodiesterases and their involvement in receptor‐mediated cell signaling important for capacitation." Molecular reproduction and development 71.4 (2005): 495-508. PMID15856425
|
Immunofluorescence, Western Blot; Mouse |
Publishing research using PD8B-201AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
---|---|---|---|---|
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PD8B-201AP | |||
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P-PD8B | |||
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PD8B-BIOTIN | |||
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PC-PD8B | |||
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