General Information |
|
Product |
Nkx2.2 Antibody FITC-Conjugated |
Description |
FITC-Conjugated homeobox protein Nkx-2.2 Antibody C-epitope |
Verified Applications |
ELISA, IMM, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
C-epitope synthetic peptide taken within amino acid region 200-273 on human homeobox protein Nkx-2.2 |
Accession # |
NCBI: NP_002500 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.68-0.70 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Determinant |
C-epitope |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:4,000 |
ELISA |
1:4,000 |
Immunoprecipitation |
1:150 |
Western Blot |
1:500 |
|
|
Uniprot # |
O95096 |
Overview |
Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity). |
Molecular Function |
Chromatin binding; transcription coactivator activity; Developmental Protein; Transcription regulation; brain development |
Subcellular Location |
Nucleus |
Expression |
Interacts with OLIG2 |
Structure |
Belongs to the NK-2 homeobox family. Contains 1 homeobox DNA-binding domain. The homeodomain is essential for interaction with OLIG2. |
Alternative Nomenclature |
Homeobox protein NK 2 homolog B antibody NK 2 homolog B antibody NK2 homeobox 2 antibody NK2 transcription factor like protein B antibody NK2 transcription factor related locus 2 antibody NKX2-2 antibody NKX22 antibody Nkx2b antibody tinman antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
NKX2-212AP | |||
|
P-NKX2.c | |||
|
NKX2.c-BIOTIN | |||
|
PC-NKX2 | |||
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