General Information |
|
Product |
MAPK13 Positive Control |
Description |
Western Blot Positive Control Mitogen-activated protein kinase 13 Antibody |
Verified Applications |
WB |
Immunogen |
Purified protein |
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|
Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
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Western Blot |
1:500 |
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Uniprot # |
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Overview |
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK13 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. MAPK13 is one of the less studied p38 MAPK isoforms. |
Molecular Function |
Kinase, Serine/threonine-protein kinase, Transferase |
Subcellular Location |
Cytosol |
Expression |
Expressed in testes, pancreas, small intestine, lung and kidney. Abundant in macrophages, also present in neutrophils, CD4+ T-cells, and endothelial cells. |
Structure |
The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases. |
Alternative Nomenclature |
MAP kinase 13 antibody MAPK 13 antibody Mitogen activated protein kinase 13 antibody PRKM13 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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MAPK13-101AP | |||
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MAPK13-BIOTIN | |||
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MAPK13-FITC | |||
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P-MAPK13 | |||
Display accessory details |
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