General Information |
|
Product |
GADD34 Antibody FITC |
Description |
FITC-Conjugated Growth arrest and DNA damage-inducible protein GADD34 Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat Predicted: Bovine, Monkey |
Immunogen |
Synthetic peptide corresponding to internal sequence of amino acids 380-400 of Human GADD34, covalently modified and coupled to a carrier protein.
Sequence: PATGVFLKSWVYQPGEDTEEE |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.58 µg/µl in antibody stabilization buffer |
Conjugate |
FITC. Ex: 493nm, Em: 528nm |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:800-1:1,000 |
ELISA |
1:800-1:1,000 |
Immunohistochemistry | 1:50-1:150 |
Immunoprecipitation | 1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Recruits serine/threonine-protein phosphatase PP1 to dephosphorylate translation initation factor eIF2A/EIF2S1. This reverses shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. |
Molecular Function |
Apoptosis; Stress Response; Translation regulation |
Subcellular Location |
Endoplasmic Reticulum membrane; Peripheral membrane protein; Cytoplasmic side; Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic Side |
Expression |
induced by methyl methanesulfonate and ionizing irradiation. Apoptosis is induced by interluekin 24 in melanoma cells |
Structure |
belongs to PPP1R15 family. |
Alternative Nomenclature |
Apoptosis associated protein antibody GADD 34 antibody Growth arrest and DNA-damage-inducible 34 antibody Myeloid differentiation primary response protein MyD116 homolog antibody PPP1R15A antibody Protein phosphatase 1 regulatory (inhibitor) subunit 15A antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
GADD34-101AP | |||
|
P-GADD34 | |||
|
GADD34-BIOTIN | |||
|
PC-GADD34 | |||
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