General Information |
|
Product |
Dnmt3a Antibody |
Description |
Affinity Purified DNA (cytosine-5)-methyltransferase 3A Antibody |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Mouse, Rat |
Immunogen |
Synthetic peptide corresponding to amino acids within region 100-150 on mouse DNA (cytosine-5)-methyltransferase 3A protein. |
|
|
Quantity |
100 µg |
Concentration |
0.5-1.5 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Conjugate |
Unconjugated |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Storage |
-20°C for long term storage |
|
|
ELISA |
1:10,000 |
Immunocytochemistry |
1:50-1:100 |
Immunofluorescence |
1:50-1:100 |
Immunohistochemistry |
1:50-1:100 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Subcellular Location |
Chromosome, Cytoplasm, Nucleus |
Expression |
Isoform 1 is expressed ubiquitously at low levels. Expression of isoform 2 is restricted to tissues containing cells which are undergoing active de novo methylation, including spleen, testis and thymus. |
Structure |
The PWWP domain is essential for targeting to pericentric heterochromatin. It specifically recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3). |
Alternative Nomenclature |
DNA (cytosine 5) methyltransferase 3 alpha antibody DNA (cytosine 5) methyltransferase 3A antibody DNA cytosine methyltransferase 3A2 antibody DNA methyltransferase 3 alpha antibody DNA methyltransferase HsaIIIA antibody DNA MTase HsaIIIA antibody DNM3A_HUMAN antibody DNMT 3a antibody DNMT antibody DNMT3A2 antibody M.HsaIIIA antibody MCMT antibody OTTHUMP00000201149 antibody TBRS antibody |
Protein information supplied by UniProt.
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