General Information |
|
Product |
Adenylate Cyclase 1 Antibody FITC-Conjugated |
Verified Applications |
ELISA, WB |
Host |
Rabbit |
Species Cross Reactivity |
Mouse, Rat |
Immunogen |
Synthetic peptide corresponding to conserved sequence at or near C terminal end of protein that is unique to rat/mouse Adenylyl Cyclase 1 protein. |
Accession # |
GenBank: AAC29478 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.72 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina |
Molecular Function |
ATP-binding, Calmodulin-binding, Magnesium, Metal-binding, Nucleotide-binding |
Subcellular Location |
Membrane; Multi-pass membrane protein. Cytoplasm |
Expression |
Expressed throughout inner ear development |
Structure |
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Contains 2 guanylate cyclase domains. |
Alternative Nomenclature |
3'5' cyclic AMP synthetase antibody ADCY1 antibody adenyl cyclase antibody Adenylate cyclase 1 antibody ATP pyrophosphate lyase antibody Brain adenylate cyclase 1 antibody Ca(2+)/calmodulin activated adenylyl cyclase antibody EC 4.6.1.1 antibody |
Protein information supplied by UniProt
Fabgennix Adenylate cyclase 1 Antibody has been used in 3 Publications |
|
Nakamura, Akio, Makoto Miyagawa, and Yukishige Yanagawa. "Modulation of 11β-hydroxysteroid dehydrogenase 1 by β2-adrenoceptor in the ischaemia-reperfused rat kidney." Nephrology Dialysis Transplantation 27.9 (2012): 3456-3464. PMID22187316
|
Western Blot; Rat |
Nakamura, Akio, Ryo Niimi, and Yukishige Yanagawa. "Protection from sepsis-induced acute renal failure by adenoviral-mediated gene transfer of β2-adrenoceptor†." Nephrology Dialysis Transplantation (2009): gfp561. PMID19887504
|
Western Blot; Rat |
Younes, Antoine et al. “Ca2+-Stimulated Basal Adenylyl Cyclase Activity Localization in Membrane Lipid Microdomains of Cardiac Sinoatrial Nodal Pacemaker Cells.” The Journal of Biological Chemistry 283.21 (2008): 14461–14468. PMC2386925
|
Dot Blot; Rabbit |
Publishing research using PAC-101AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
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PAC-101AP | |||
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P-PAC1 | |||
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PAC1-BIOTIN | |||
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PC-PAC1 | |||
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