General Information
|
|
Product
|
ABHD2 Peptide
|
Description
|
Antigenic Blocking Peptide a/b hydrolase II
|
Verified Applications
|
Immunodepletion, Immunocompetition
|
Peptide Description
|
Synthetic peptide taken within amino acid region 200-250 on mouse a/b hydrolase II protein.
|
Accession #
|
GenBank: AAQ12022.1
|
Physical Properties
|
|
Quantity
|
250 µg
|
Volume
|
100 µl
|
Form
|
Antigenic Blocking Peptide
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
Competition/Depletion assay
|
Refer to competition assay protocol
|
Protein
|
Uniprot #
|
Q9QXM0
|
Overview
|
Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Involved in acrosomal reaction (PubMed:26989199). May also play a role in smooth muscle cells migration.
|
Molecular Function
|
Hydrolase, Serine esterase
|
Subcellular Location
|
Cell membrane; Single-pass type II membrane protein
Cytoplasmic vesicle › secretory vesicle › acrosome membrane
|
Expression
|
Widely expressed with higher expression in testis. Expressed by vascular smooth muscle cells, non vascular smooth muscle cells and heart.
|
Structure
|
Signal-anchor, Transmembrane, Transmembrane helix
|
Alternative Nomenclature
|
2210009N18Rik antibody
abhydrolase domain containing 2 antibody
alpha/beta hydrolase domain containing protein 2 antibody
HS1 2 antibody
LABH2 antibody
Lung alpha/beta hydrolase 2 antibody
PHPS1 2 antibody
protein PHPS1-2 antibody
|
|
|