General Information
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Product
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alpha Synuclein Positive Control
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Description
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Western Blot Positive Control alpha-synuclein isoform NACP112
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Verified Applications
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WB
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Immunogen
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Purified Protein
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Accession #
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NCBI: NP_009292
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Physical Properties
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Quantity
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5 Applications
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Volume
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Inquire
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Form
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Western Blot Positive Control
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Storage
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-20⁰C for long term storage
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Application Protocol
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Western Blot
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1:500
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Protein
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Uniprot #
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P37840
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Overview
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May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
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Molecular Function
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Alpha-tubulin binding, Calcium-ion binding, copper ion binding
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Subcellular Location
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cytoplasm, Membrane, Nucleus, Cell junction > synapse
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Expression
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Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.
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Structure
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Soluble monomer which can form filamentous aggregates. Interacts with UCHL1 (By similarity). Interacts with phospholipase D and histones
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Alternative Nomenclature
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Alpha synuclein antibody
MGC105443 antibody
MGC110988 antibody
MGC127560 antibody
NACP antibody
PARK 1 antibody
PARK 4 antibody
PD 1 antibody
SNCA antibody
SYN antibody
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