General Information
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Product
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GPCR GPR8 Antibody FITC-Conjugated
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Description
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FITC-Conjugated Neuropeptide B/W receptor type 2 Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey
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Immunogen
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Synthetic peptide taken within amino acid region 280-333 on human Neuropeptides B/W receptor type 2 protein.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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Immunohistochemistry |
1:50-1:100 |
Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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P48146
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Overview
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Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals.
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Molecular Function
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G-protein coupled receptor, Receptor, Transducer.
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Subcellular Location
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Cell membrane; Multi-pass membrane protein.
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Expression
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Detected at high levels in caudate nucleus, hyppocampus and amygdala; at moderate levels in the adult brain, thalamus, parietal cortex, pituitary gland, adrenal gland and lymph nodes.
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Structure
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Belongs to the G-protein coupled receptor 1 family.
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Alternative Nomenclature
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G protein coupled receptor 8
GPR8
Neuropeptides B/W receptor type 2
NPBWR2
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