General Information |
|
Product |
CD68 Peptide |
Description |
Antigenic Blocking Peptide CD68 / Macrosialin |
Verified Applications |
Immunodepletion, Immunocompetition |
Peptide Description |
Synthetic peptide taken within amino acid region 240-290 on mouse CD68 / Macrosialin protein. |
Accession # |
NCBI: NP_055843 |
|
|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
|
|
Competition/Depletion assay |
|
|
|
Uniprot # |
|
Overview |
Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. |
Molecular Function |
cellular response to organic substance |
Subcellular Location |
Endosome membrane; Single-pass type I membrane protein |
Expression |
Expressed in tissue macrophages and to a lesser extent in dendritic cells. |
Structure |
Belongs to the LAMP family. |
Alternative Nomenclature |
CD 68 antibody CD68 antigen antibody CD68 molecule antibody DKFZp686M18236 antibody gp11 antibody Gp110 antibody LAMP4 antibody MACROPHAGE ANTIGEN CD68 antibody Macrosialin antibody SCARD1 antibody Scavenger receptor class D member 1 antibody |
Protein information supplied by UniProt.
Product | Note | Status | Price | |
---|---|---|---|---|
|
CD68-101AP | |||
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CD68-BIOTIN | |||
|
CD68-FITC | |||
|
PC-CD68 | |||
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