General Information |
|
Product |
cGKI Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated cGMP-dependent protein kinase 1 Antibody |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 609-659 on human protein kinase G alpha subunit. |
Accession # |
NCBI: NP_001091982.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.64-0.72 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Serine/threonine protein kinase that acts as key mediator of the nitric oxide (NO)/cGMP signaling pathway. GMP binding activates PRKG1, which phosphorylates serines and threonines on many cellular proteins. |
Molecular Function |
Kinase, Serine/threonine-protein kinase, Transferase |
Subcellular Location |
Cytoplasm |
Expression |
Primarily expressed in lung and placenta |
Structure |
Isoform alpha: parallel homodimer or heterodimer and also heterotetramer. Interacts directly with PPP1R12A. Non-covalent dimer of dimer of PRKG1-PRKG1 and PPP1R12A-PPP1R12A. |
Alternative Nomenclature |
cGK 1 antibody cGKI alpha antibody CGKI antibody cGKI beta antibody cGMP-dependent protein kinase 1 antibody DKFZp686K042 antibody FLJ36117 antibody KGPB antibody MGC71944 antibody pkg antibody PRKG1 antibody PRKGR1A antibody PRKGR1B antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-PKGA | |||
|
PKGA-101AP | |||
|
PKGA-FITC | |||
|
PC-PKGA | |||
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