General Information |
|
Product |
Synaptophysin Antibody BIOTIN-Conjugated C-epitope |
Verified Applications |
CM, ELISA, ICC, IF, IHC, IMM, WB |
Host |
Rabbit |
Species Cross Reactivity |
Chicken, Human, Monkey, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 250-350 on human Synaptophysin protein. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.60-0.62 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Determinant |
C-epitope |
Storage |
-20⁰C for long term storage |
|
|
Confocal Microscopy |
1:100 |
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunocytochemistry |
1:100 |
Immunofluorescence |
1:100 |
Immunohistochemistry |
1:100 |
Immunoprecipitation |
1:125 |
Western Blot |
1:1,000 |
|
|
Uniprot # |
|
Overview |
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity). |
Molecular Function |
Cholesterol binding, protein self-association, transporter activity |
Subcellular Location |
Cytoplasmic vesicle › secretory vesicle › synaptic vesicle membrane; Multi-pass membrane protein. Cell junction ›synapse › synaptosome |
Expression |
Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype. |
Structure |
Homohexamer or homotetramer. Interacts with SRCIN1. |
Alternative Nomenclature |
Major synaptic vesicle protein P38 antibody MRXSYP antibody Syn p38 antibody Synaptophysin antibody SYP antibody SYPH antibody SypI antibody |
Protein information supplied by UniProt
Fabgennix Synaptophysin Antibody has been used in 2 Publications |
|
Morita, Ippei, et al. "HNK-1 (Human natural killer-1) glyco-epitope is essential for normal spine morphogenesis in developing hippocampal neurons." Neuroscience 164.4 (2009): 1685-1694. PMID19796667
|
Immunofluorescence, Immunoprecipitation, Western Blot; Rat |
Morita, Ippei et al. “HNK-1 Glyco-Epitope Regulates the Stability of the Glutamate Receptor Subunit GluR2 on the Neuronal Cell Surface.” The Journal of Biological Chemistry 284.44 (2009): 30209–30217. PMC2781576
|
Immunoprecipitation, Western Blot; Mouse |
Publishing research using SYN-101AP? Please let us know, we can cite the reference in this datasheet.
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