General Information
|
|
Product
|
YME1L1 Peptide
|
Description
|
Antigenic Blocking Peptide ATP-dependent metalloprotease YME1L1 Antibody
|
Verified Applications
|
Immunodepletion, Immunocompetition
|
Peptide Description
|
Synthetic peptide taken within amino acid region 720-773 on human ATP-dependent metalloprotease YME1L1 protein.
|
Physical Properties
|
|
Quantity
|
250 µg
|
Volume
|
100 µl
|
Form
|
Antigenic Blocking Peptide
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
Competition/Depletion assay
|
Refer to competition assay protocol
|
Protein
|
Uniprot #
|
Q96TA2
|
Overview
|
Putative ATP-dependent protease which plays a role in mitochondrial protein metabolism. Ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins. Requires to control the accumulation of nonassembled respiratory chain subunits (NDUFB6, OX4 and ND1). Seems to act in the processing of OPA1.
|
Molecular Function
|
Hydrolase, Metalloprotease, Protease
|
Subcellular Location
|
Mitochondrion inner membrane
|
Expression
|
High expression in cardiac and skeletal muscle mitochondria.
|
Structure
|
In the N-terminal section; belongs to the AAA ATPase family.
In the C-terminal section; belongs to the peptidase M41 family.
|
Alternative Nomenclature
|
ATP dependent metalloprotease FtsH1 homolog antibody
ATP-dependent zinc metalloprotease YME1L1 antibody
FTSH1 antibody
Meg-4 antibody
MEG4 antibody
PAMP antibody
Presenilin-associated metalloprotease antibody
UNQ1868/PRO4304 antibody
YME1 like 1 antibody
YME1-like protein 1 antibody
YME1L antibody
|
|
|