General Information

Product

EHD4 Antibody

Description

Affinity Purified EH domain-containing protein 4 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse Rat

Immunogen

Synthetic peptide taken within amino acid region 420-450 on EH-domain containing 4 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9H223

Overview

Plays a role in early endosomal transport

Molecular Function

ATP binding;GTPase activity;nucleic acid binding;calcium ion binding;GTP binding

Subcellular Location

Cell membrane, Endosome, Membrane

Expression

Highly expressed in pancreas and heart.

Structure

Homooligomer, and heterooligomer with EHD1, EHD2 and EHD3

Alternative Nomenclature

EH domain containing 4 antibody

Hepatocellular carcinoma associated protein 10/11 antibody

HCA11 antibody

HGNC:3245 antibody

Ortholog of rat pincher antibody

PAST4 antibody

General Information

Product

LAMP1 Antibody

Description

Affinity Purified Lysosome-associated membrane glycoprotein 1 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 300-350 on human LAMP1 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P11279

Overview

Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.

Molecular Function

Enzyme binding

Subcellular Location

Cell membrane, single-pass type I membrane protein, endosome membrane, lysosome membrane (Note:This protein shuttles between lysosomes, endosomes, and plasma membrane. Colocalizes with OSBPL1A at the late endosome)

Alternative Nomenclature

CD107 antigen like family member A antibody

LAMP 1 antibody

LAMPA antibody

LGP120 antibody

lgpA antibody

Lysosomal Associated Membrane Protein 1 antibody

General Information

Product

SEC24A Antibody

Description

Affinity Purified Protein transport protein Sec24A Antibody

Verified Applications

CM, ELISA, ICC/IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 810-850 on SEC24A protein.

Accession #

NCBI:  NP_001099250.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.61-0.64 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

D3ZZA8

Molecular Function

Zinc ion bonding

Alternative Nomenclature

protein transport protein Sec24A antibody

SEC24 related gene family member A antibody

SEC24 related protein A antibody

SEC24 S cerevisiae related gene family member A antibody

General Information

Product

SEC24D Antibody

Description

Affinity Purified Sec24d protein Antibody

Verified Applications

CM, ELISA, ICC, IHC, IF, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Predicted:  Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 860-920 on human SEC24D protein.

Accession #

NCBI:  NP_055637

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.59 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

Dot Blot

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

O94855

Molecular Function

Zinc ion bonding

Alternative Nomenclature

KIAA0755 antibody

Protein transport protein Sec24D antibody

SEC24 family member D antibody

SEC24 related gene family, member D antibody

SEC24-related protein D antibody

General Information

Product

Alpha SNAP Antibody

Description

Affinity Purified alpha-soluble NSF attachment protein Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Pig, Rat

Immunogen

Synthetic peptide taken within amino acid region 195-245 on human alpha-soluble NSF attachment protein.

Accession #

GenBank: AAC80170.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.56 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P54920

Overview

Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

Molecular Function

Soluble NSF attachment protein activity; Syntaxin binding

Subcellular Location

Membrane, peripheral membrane protein

Structure

Interacts with PRKCABP, and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. Found in a complex with VAMP8. Component of a SNARE-like complex.

Alternative Nomenclature

Alpha soluble NSF attachment protein antibody

N ethylmaleimide sensitive factor attachment protein alpha antibody

NAPA antibody

SNAP alpha antibody

SNAPA antibody

General Information

Product

VPS26 Antibody

Description

Affinity Purified Vacuolar protein sorting-associated protein 26A Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acids 315-375 on human VPS26 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.56 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

O75436

Overview

Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3.

Molecular Function

protein transporter activity

Subcellular Location

cytoplasm, endosome membrane, preipheral membrane protein (Note: Localizes to tubular profiles adjacent to endosomes. Predominantly found in early not late endosomes)

Expression

Down-regulated in Alzheimer disease. No polymorphism or variant is however associated with Alzheimer disease for VPS26A.

Alternative Nomenclature

FLJ12930 antibody

FLJ12930 antibody

HB 58 antibody

Hbeta 58 antibody

Hbeta 58 homolog antibody

MGC94168 antibody

PEP 8A antibody

Vacuolar protein sorting 26 A antibody

Vacuolar protein sorting 26 homolog A yeast antibody

Vacuolar protein sorting associated protein 26A antibody

Vesicle protein sorting 26A antibody

VPS 26 antibody

VPS 26A antibody

General Information

Product

GPIP137 Antibody

Description

Affinity Purified Caprin-1 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 200-250 on human Caprin 1 protein.

Accession #

NCBI: NP_976240

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.54 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q14444

Overview

Involved in transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types.

Molecular Function

RNA-binding; Differentiation

Subcellular Location

Cytoplasm; Cell projection

Expression

Ubiquitous

Structure

May form homomultimers.  Binds with several mRNAs.  Directly interacts with G3BP1 in cytoplasmic RNA granules.

Alternative Nomenclature

Cell cycle-associated protein 1 antibody

GPI-anchored protein p137 antibody

M11S1 antibody

Membrane component chromosome 11 surface marker 1 antibody

RNA granule protein 105 antibody

General Information

Product

CTR1 / SLC31A1 Antibody

Description

Affinity Purified High affinity copper uptake protein 1 Antibody N-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

N-epitope synthetic peptide corresponding to amino acids 1-50 of Human SLC31A1 / CTR1 protein.

Sequence:

MDHSHHMGMS YMDSNSTMQP SHHHPTTSAS HSHGGGDSSM MMMPMTFYFG

Accession #

NCBI:  NP_001850.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

O15431

Overview

High-affinity, saturable copper transporter involved in dietary copper uptake.

Molecular Function

Copper ion transmembrane transporter activity, copper uptake transmembrane transporter activity

Subcellular Location

Cell membrane; Multi-pass membrane protein

Structure

Homotrimer

Alternative Nomenclature

Copper transport 1 homolog 

COPT1 

CTR1 

hCTR1 

High affinity copper uptake protein 1 

SLC31A1 

Solute carrier family 31 member 1 

General Information

Product

Dopamine Transporter Antibody

Description

Affinity Purified Sodium-dependent dopamine transporter Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 550-600 on SLC6A3 protein.

Accession #

NCBI: NP_001035.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20°C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q01959

Overview

Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.

Molecular Function

dopamine:sodium symporter activity; monoamine transmembrane transporter activity

Subcellular Location

Cell membrane; Plasma Membrane; Multi-pass membrane protein; neuronal cell body; axon; cytoplasm

Expression

substantia nigra in Brain

Structure

Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family,SLC6A3 subfamily has a Transmembrane helix domain.

Alternative Nomenclature

DA transporter antibody

PKDYS antibody

SLC6A3 antibody

Sodium dependent dopamine transporter antibody

Solute carrier family 6 (neurotransmitter transporter dopamine), member 3 antibody

Variable number tandem repeat (VNTR) antibody

General Information

Product

TOMM7 Antibody

Description

Affinity Purified Mitochondrial import receptor subunit TOM7 homolog Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Pig, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human Mitochondrial import receptor subunit TOM7 homolog protein.

Accession #

NCBI:  NP_061932.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q9P0U1

Overview

Required for assembly and stability of the TOM complex. Positive regulator of PARK2 translocation to damaged mitochondria. Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria.

Molecular Function

Cellular protein metabolic process; Protein targeting to mitochondrion

Subcellular Location

Membrane, Mitochondrion, Mitochondrion outer membrane

Structure

Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which consists of at least 7 different proteins (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70).

Alternative Nomenclature

Mitochondrial import receptor subunit TOM7 homolog antibody
TOM7 antibody