General Information
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Product
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PD-L1 Positive Control
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Description
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Western Blot Positive Control Programmed cell death 1 ligand 1 Antibody
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Verified Applications
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WB
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Immunogen
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Purified protein
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Accession #
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NCBI: NP_054862
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Physical Properties
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Quantity
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5 Applications
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Volume
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Inquire
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Form
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Western Blot Positive Control
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Purification Method
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Immobilized antigen affinity chromatography
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Storage
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-20⁰C for long term storage
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Application Protocol
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9NZQ7
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Overview
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Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
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Molecular Function
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Receptor
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Subcellular Location
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Isoform 1 : Cell membrane; Single-pass type I membrane protein
Isoform 2 : Endomembrane system; Single-pass type I membrane protein
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Expression
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Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes.
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Structure
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Belongs to the immunoglobulin superfamily. BTN/MOG family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
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Alternative Nomenclature
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B7 H antibody
B7 homolog 1 antibody
CD 274 antibody
PD L1 antibody
PDCD1 ligand 1 antibody
PDCD1L1 antibody
PDCD1LG1 antibody
PDL 1 antibody
Programmed death ligand 1 antibody
RGD1566211 antibody
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