General Information
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Product
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Bestrophin 1 Antibody FITC-Conjugated
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Dog, Human, Monkey
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Immunogen
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Synthetic peptide taken within amino acid region 530-580 on canine Bestrophin 1 protein.
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Accession #
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NCBI: NP_001091014.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.75 µg/µl in antibody stabilization buffer
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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A5H7G8
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Overview
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Forms calcium sensitive chloride channels. Highly permeable to bicarbonate.
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Molecular Function
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Ion transport; Sensory transduction; Transport; Vision
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Subcellular Location
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Cell membrane; Multi-pass membrane protein; Basolateral cell membrane
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Expression
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Predominantly expressed in the basolateral membrane of the retinal pigment epithelium
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Structure
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Tetramer or pentamers
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Alternative Nomenclature
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ARB antibody
BEST 1 antibody
BEST antibody
Best disease antibody
Best macular dystrophy antibody
Best1V1Delta2 antibody
BMD antibody
mBest1 antibody
RP50 antibody
TU15B antibody
Vitelliform macular dystrophy 2 antibody
Vitelliform macular dystrophy protein 2 antibody
VMD 2 antibody
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