General Information
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Product
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TLR1 Peptide
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Description
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Antigenic Blocking Peptide Toll-like receptor 1
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Verified Applications
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Immunocompeition, Immunodepletion
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Peptide Description
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Synthetic peptide taken within amino acid region 200-250 on mouse toll-like receptor 1 protein.
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Accession #
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NCBI: NP_109607.1
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q9EPQ1
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Overview
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Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.
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Molecular Function
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Receptor, Transmembrane signaling receptor activity, triacyl lipopeptide binding
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Subcellular Location
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Cell membrane; Single-pass type I membrane protein, Cytoplasmic vesicle > phagosome membrane; Single-pass type I membrane protein
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Structure
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Binds MYD88 (via TIR domains). Interacts (via extracellular domain) with TLR2. Ligand binding induces the formation of a heterodimer with TLR2. Interacts with CNPY3.
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Alternative Nomenclature
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CD281 antibody
KIAA0012 antibody
LPRS5 antibody
rsc786 antibody
Similar to Drosophila Toll protein antibody
TIL antibody
TIL. LPRS5 antibody
Tlr1 antibody
Toll (Drosophila) homolog antibody
Toll like receptor 1 antibody
Toll/Interleukin 1 receptor like antibody
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