General Information |
|
Product |
Bestrophin Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated Bestrophin 1 Antibody Mid-Region |
Verified Applications |
CM, ELISA, IF, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Monkey, Mouse, Rat |
Immunogen |
Mid-Region Synthetic peptide corresponding to unique amino acid sequences on human Bestrophin 1 protein. |
Accession # |
NCBI: NP_004174.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.65 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Determinant |
Mid-Region |
Storage |
-20⁰C for long term storage |
|
|
Confocal Microscopy |
1:100 |
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunocytochemistry |
1:100 |
Immunofluorescence |
1:100 |
Immunohistochemistry |
1:100 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Forms calcium sensitive chloride channels. Highly permeable to bicarbonate. |
Molecular Function |
Ion transport; Sensory transduction; Transport; Vision |
Subcellular Location |
Cell membrane; Multi-pass membrane protein; Basolateral cell membrane |
Expression |
Predominantly expressed in the basolateral membrane of the retinal pigment epithelium |
Structure |
Tetramer or pentamers |
Alternative Nomenclature |
ARB antibody BEST 1 antibody BEST antibody Best disease antibody BEST1 antibody Bestrophin1 antibody BMD antibody mBest1 antibody RP50 antibody TU15B antibody Vitelliform macular dystrophy 2 antibody VMD2 antibody |
Protein information supplied by UniProt
Fabgennix Bestrophin 1 Antibody has been used in 5 Publications |
|
Vossmerbaeumer, Urs, et al. "Retinal Pigment Epithelial Phenotype Induced In Human Adipose Tissue-Derived Mesenchymal Stromal Cells." Cytotherapy (Taylor & Francis Ltd)11.2 (2009): 177-188. PMID19241195
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Immunocytochemical fluorescence, Western Blot; Human |
Marsey, Laura L, and John P Winpenny. “Bestrophin Expression and Function in the Human Pancreatic Duct Cell Line, CFPAC-1.” The Journal of Physiology 587.Pt 10 (2009): 2211–2224. PMC2697294 |
Confocal Microscopy, Immunofluorescence, Western Blot; Human |
Vossmerbaeumer, Urs, et al. "Cultivation and differentiation characteristics of human limbal progenitor cells." Tissue and Cell 40.2 (2008): 83-88. PMID18061639 |
Immunohistochemistry; Human |
Vossmerbaeumer, Urs, et al. "Induction of retinal pigment epithelium properties in ciliary margin progenitor cells." Clinical & experimental ophthalmology 36.4 (2008): 358-366. |
Immunohistochemistry; Rat |
Duta, Valentin, et al. "The role of bestrophin in airway epithelial ion transport." FEBS letters 577.3 (2004): 551-554.
|
Immunodepletion, Immunohistochemistry, Western Blot; Human |
Publishing research using BEST-101AP? Please let us know, we can cite the reference in this datasheet.
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BEST-112AP | |||
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BEST1.2-FITC | |||
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PC-BEST1 | |||
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