General Information |
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Product |
Indoleamine 2, 3-dioxygenase 2 Peptide |
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Description |
Antigenic Blocking Peptide Indoleamine 2,3-dioxygenase 2 Antibody |
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Verified Applications |
Immunodepletion, Immunocompetition |
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Peptide Description |
Synthetic peptide taken within amino acid region 370-420 on human Indoleamine 2,3-dioxygenase 2 protein. |
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Quantity |
250 µg |
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Volume |
100 µl |
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Form |
Antigenic Blocking Peptide |
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Storage |
-20⁰C for long term storage |
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Competition/Depletion assay |
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Uniprot # |
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Overview |
Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway (PubMed:17671174). Involved in immune regulation. May not play a significant role in tryptophan-related tumoral resistance. |
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Molecular Function |
heme binding indoleamine 2,3-dioxygenase activity metal ion binding tryptophan 2,3-dioxygenase activity |
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Subcellular Location |
cytosol |
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Expression |
Detected in liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon (PubMed:17671174). Also expressed at low level in testis and thyroid. Not expressed in the majority of human tumor samples (>99%). |
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Structure |
Belongs to the indoleamine 2,3-dioxygenase family. |
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Alternative Nomenclature |
3-dioxygenase antibody I23O1_HUMAN antibody IDO 2 antibody IDO antibody IDO-2 antibody IDO2 antibody INDO antibody indolamine 2,3 dioxygenase antibody Indole 2 3 dioxygenase antibody indoleamine 2 3 dioxygenase 1 antibody indoleamine 2 3 dioxygenase antibody Indoleamine 2,3-dioxygenase 1 antibody Indoleamine pyrrole 2 3 dioxygenase antibody Indoleamine-pyrrole 2 antibody |
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Protein information supplied by UniProt.
Product | Note | Status | Price | |
---|---|---|---|---|
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IDO2-FITC | |||
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IDO2-201AP | |||
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IDO2-BIOTIN | |||
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PC-IDO2 | |||
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