General Information |
|
Product |
TLR1 Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated Toll-like receptor 1 precursor Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Mouse, Rat Predicted: Human |
Immunogen |
Synthetic peptide taken within amino acid region 200-250 on mouse toll-like receptor 1 protein. |
Accession # |
NCBI: NP_109607.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.55-0.67 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:20,000 |
Immunocytochemistry |
1:100 |
Immunofluorescence |
1:100 |
Immunohistochemistry |
1:100 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. |
Molecular Function |
Receptor, Transmembrane signaling receptor activity, triacyl lipopeptide binding |
Subcellular Location |
Cell membrane; Single-pass type I membrane protein, Cytoplasmic vesicle > phagosome membrane; Single-pass type I membrane protein |
Structure |
Binds MYD88 (via TIR domains) (By similarity). Interacts (via extracellular domain) with TLR2. Ligand binding induces the formation of a heterodimer with TLR2 (By similarity). Interacts with CNPY3. |
Alternative Nomenclature |
CD281 antibody KIAA0012 antibody LPRS5 antibody rsc786 antibody Similar to Drosophila Toll protein antibody TIL antibody TIL. LPRS5 antibody Tlr1 antibody Toll (Drosophila) homolog antibody Toll like receptor 1 antibody Toll/Interleukin 1 receptor like antibody |
Protein information supplied by UniProt
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---|---|---|---|---|
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P-TLR1 | |||
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TLR-101AP | |||
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TLR1-FITC | |||
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PC-TLR1 | |||
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