ASIC2 Positive Control

Product no.: PC-ASIC2

General Information
Product	ASIC2 Positive Control
Description	Western Blot Positive Control Acid-sensing ion channel 2 Antibody
Verified Applications	WB
Immunogen	Purified protein.
Physical Properties
Quantity	5 Applications
Volume	Inquire
Form	Western Blot Positive Control
Storage	-20⁰C for long term storage
Application Protocol
Western Blot	1:2,500-1:5,000
Protein
Uniprot #	Q16515
Overview	Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li+ and K+. Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.
Molecular Function	acid-sensing ion channel activity; ion gated channel activity; ligand-gated sodium channel activity
Subcellular Location	Cell membrane; Multi-pass membrane protein
Expression	Brain and spinal cord. Isoform 1 is also detected in testis, liver, colon and ovary.
Structure	Homotrimer or heterotrimer with other ASIC proteins.
Alternative Nomenclature	ACCN1 antibody Acid sensing ion channel 2 antibody Amiloride sensitive brain sodium channel antibody Amiloride sensitive cation channel 1 neuronal antibody ASIC2 antibody BNaC1 antibody Brain sodium channel 1 antibody Degenerin antibody Mammalian degenerin homolog antibody MDEG antibody Neuronal amiloride sensitive cation channel 1 antibody

Protein information supplied by UniProt.