General Information
|
|
Product
|
CD39 Antibody BIOTIN
|
Description
|
BIOTIN-Conjugated EctoNucleoside TriPhosphate Diphosphohydrolase 1 Antibody
|
Verified Applications
|
ELISA, IHC, IP, WB
|
Host
|
Rabbit
|
Species Cross Reactivity
|
Human, Mouse, Rat
|
Immunogen
|
Synthetic peptide taken within amino acid region 440-490 on human EctoNucleoside TriPhosphate Diphosphohydrolase 1.
|
Physical Properties
|
|
Quantity
|
100 µg
|
Volume
|
200 µl
|
Concentration
|
0.5-1.5 µg/µl in antibody stabilization buffer
|
Immunoglobulin
|
IgG
|
Form
|
BIOTIN-Conjugated
|
Purification Method
|
Immobilized antigen affinity chromatography
|
Clonality
|
Polyclonal
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
ELISA
|
1:50,000
|
Immunohistochemistry |
1:50-1:200 |
Immunoprecipitation
|
1:200
|
Western Blot
|
1:2,500-1:5,000
|
Protein
|
Uniprot #
|
P49961
|
Overview
|
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP.
|
Molecular Function
|
blood coagulation
cell adhesion
nucleobase-containing small molecule catabolic process
|
Subcellular Location
|
Membrane; Multi-pass membrane protein
|
Expression
|
Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. Isoform 1 and isoform 3 are present in both placenta and umbilical vein, whereas isoform 2 is present in placenta only.
|
Structure
|
Belongs to the GDA1/CD39 NTPase family.
|
Alternative Nomenclature
|
ATPDase antibody
CD 39 antibody
CD39 antigen antibody
Ecto apyrase antibody
Ecto ATP diphosphohydrolase antibody
Ecto-ATPase 1 antibody
Ecto-ATPDase 1 antibody
Ectonucleoside triphosphate diphosphohydrolase 1 antibody
ENTPD1 antibody
Lymphoid cell activation antigen antibody
NTPDase 1 antibody
SPG64 antibody
|
|
|