General Information |
|
Product |
SOX2 Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated Sex determing region Y-box 2 Antibody N-epitope |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Monkey, Mouse, Pig |
Immunogen |
Synthetic peptide taken within amino acid region 50-100 on human Sex determing region Y-box 2 protein. |
Accession # |
GenBank: AJF45879.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.55-0.75 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Determinant |
N-epitope |
Storage |
-20⁰C for long term storage |
|
|
DOT Blot |
1:10,000 |
ELISA |
1:10,000 |
Immunohistochemistry | 1:50-1:150 |
Immunoprecipitation |
1:150 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. |
Molecular Function |
Chromatin binding; DNA binding; miRNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription. |
Subcellular Location |
Nucleus |
Structure |
Interacts with ZSCAN10. Interacts with SOX3 and FGFR1. |
Alternative Nomenclature |
ANOP3 antibody cb236 antibody Delta EF2a antibody lcc antibody MCOPS3 antibody MGC148683 antibody MGC2413 antibody RGD1565646 antibody SRY (sex determining region Y) box 2 antibody SRY box containing gene 2 antibody SRY related HMG box gene 2 antibody SRY-box 2 antibody Transcription factor SOX 2 antibody ysb antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-SOX2.201 | |||
|
SOX2-201AP | |||
|
SOX2.201-FITC | |||
|
PC-SOX2 | |||
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