General Information |
|
Product |
FOLR2 Antibody |
Description |
Affinity Purified Folate receptor beta Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 1-50 on rat Folate receptor 2 protein. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
Affinity Purified |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:50,000 |
Immunohistochemistry | 1:50-1:150 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. |
Molecular Function |
Receptor |
Subcellular Location |
Cell membrane; Lipidanchor > GPI-anchor, Secreted |
Expression |
Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues. |
Structure |
Belongs to the folate receptor family. |
Alternative Nomenclature |
beta hFR antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
FOLR2-101AP | |||
|
FOLR2-FITC | |||
|
P-FOLR2 | |||
|
PC-FOLR2 | |||
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