General Information
|
|
Product
|
DAP Kinase 1 Peptide
|
Description
|
Antigenic Blocking Peptide Death-associated protein kinase 1 Antibody
|
Verified Applications
|
Immunodepletion, Immunocompetition
|
Peptide Description
|
Synthetic peptide taken within amino acid region 1370-1420 on human Death-associated protein kinase 1 protein.
|
Physical Properties
|
|
Quantity
|
250 µg
|
Volume
|
100 µl
|
Form
|
Antigenic Blocking Peptide
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
Competition/Depletion assay
|
Refer to competition assay protocol
|
Protein
|
Uniprot #
|
P53355
|
Overview
|
Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy.
|
Molecular Function
|
ATP binding
calmodulin binding
calmodulin-dependent protein kinase activity
GTP binding
identical protein binding
protein kinase activity
protein serine/threonine kinase activity
syntaxin-1 binding
|
Subcellular Location
|
Cytoskeleton
|
Expression
|
Isoform 2 is expressed in normal intestinal tissue as well as in colorectal carcinomas.
|
Structure
|
The autoinhibitory domain sterically blocks the substrate peptide-binding site by making both hydrophobic and electrostatic contacts with the kinase core.
|
Alternative Nomenclature
|
DAK1 antibody
DAP K1 antibody
DAP kinase 1 antibody
DAPK antibody
DAPK1 antibody
Death Associated Protein Kinase 1 antibody
|
|
|