General Information |
|
Product |
MAPK4 Positive Control |
Description |
Western Blot Positive Control Mitogen-activated protein kinase 4 Antibody |
Verified Applications |
WB |
Immunogen |
Purified protein |
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|
Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
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|
Western Blot |
1:500 |
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Uniprot # |
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Overview |
Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle. |
Molecular Function |
Kinase, Serine/threonine-protein kinase, Transferase |
Subcellular Location |
Cytoplasm, Nucleus |
Expression |
High expression in heart and brain. |
Structure |
Homodimer. Heterodimer with ERK3/MAPK6. Interacts with (via FRIEDE motif) MAPKAPK5. |
Alternative Nomenclature |
ERK-4 antibody MAPK4 antibody p63 MAPK antibody PRKM4 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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MAPK4-101AP | |||
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MAPK4-BIOTIN | |||
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MAPK4-FITC | |||
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P-MAPK4 | |||
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