General Information |
|
Product |
Phospho-PARP1 Antibody FITC |
Description |
Affinity Purified Phospho-specific Poly ADP-ribose polymerase 1 Antibody FITC |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 870-920 on human Phospho-specific Poly ADP-ribose polymerase 1 protein. |
Accession # |
NCBI: NP_001609 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.58 µg/µl in antibody stabilization buffer |
Form |
Affinity Purified |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunohistochemistry | 1:50-1:100 |
Immunoprecipitation | 1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
P09874 |
Overview |
Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair. Mediates glutamate, aspartate, serine, histidine or tyrosine ADP-ribosylation of proteins. |
Molecular Function |
Allosteric enzyme, DNA-binding, Glycosyltransferase, Nucleotidyltransferase, Transferase |
Expression |
Expressed in ventricular zone and 212 other cell types or tissues. |
Structure |
Homodimer; PARP-type zinc-fingers from separate PARP1 molecules form a dimer module that specifically recognizes DNA strand breaks. |
Alternative Nomenclature |
ADP-ribosyltransferase diphtheria toxin-like 1 DNA ADP-ribosyltransferase PARP1 Protein poly-ADP-ribosyltransferase PARP1 PARP1 ADPRT PPOL |
Protein information supplied by UniProt
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