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General Information
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Product
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Particulate Guanylate Cyclase C Antibody FITC-Conjugated
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Verified Applications
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CM, ELISA, ICC, IF, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase C protein.
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Accession #
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GenBank: AAA41201.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.75-1.20 µg/µl in antibody stabilization buffer
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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Confocal Microscopy
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1:200
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DB
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1:10,000
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ELISA
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1:10,000
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Immunocytochemistry
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1:200
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Immunofluorescence
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1:200
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Immunohistochemistry
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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P23897
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Overview
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Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptide guanylin.
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Molecular Function
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Lyase, Receptor
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Subcellular Location
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Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane
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Structure
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Homotrimer. Interacts via its C-terminal region with PDZK2. Interacts with the lectin chaperone VIP36
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Alternative Nomenclature
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ANP C antibody
ANPRC antibody
Atrial natriuretic peptide C type receptor antibody
Atrionatriuretic peptide receptor C antibody
C5orf23 antibody
FLJ14054 antibody
GUCY2B antibody
MGC22189 antibody
Natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) antibody
NPR 3 antibody
NPR C antibody
Guanylyl Cyclase C antibody NPR-C antibody
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Particulate Guanylate Cyclase C Antibody
Particulate Guanylate Cyclase C Peptide
Particulate Guanylate Cyclase C Antibody BIOTIN
Particulate Guanylate Cyclase C Positive Control
