General Information
|
|
Product
|
RICH2 Antibody FITC
|
Description
|
FITC-Conjugated Rho GTPase-activating protein 44 isoform 2 Antibody
|
Verified Applications
|
ELISA, IHC, IP, WB
|
Host
|
Rabbit
|
Species Cross Reactivity
|
Human, Mouse, Rat
|
Immunogen
|
Synthetic peptide corresponding to N terminal amino acids 1-60 of Mouse RICH2.
Sequence:
MKKQFNRMRQ LANQTVGRA E KTEVLSED LL QVEKRLE LVK QVSHST HKKL TACLQ GQQGA
|
Accession #
|
NCBI: NP_778168.2
|
Physical Properties
|
|
Quantity
|
100 µg
|
Volume
|
200 µl
|
Concentration
|
0.6 µg/µl in antibody stabilization buffer
|
Form
|
FITC-Conjugated
|
Clonality
|
Polyclonal
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
DB
|
1:10,000
|
ELISA
|
1:10,000
|
Immunohistochemistry |
1:50-1:150 |
Immunoprecipitation |
1:200 |
Western Blot
|
1:250-1:500
|
Protein
|
Uniprot #
|
Q5SSM3
|
Overview
|
GTPase-activating protein (GAP) that stimulates the GTPase activity of the Rho-type GTPases. Thereby controlling the Rho-type GTPases cycling between their active GTP-bound and inactive GDP bound states.
|
Molecular Function
|
GTPase activator activity, phospholipid binding, GTPase activation
|
Subcellular Location
|
Cell projection, Recycling endosome, Cell junction
|
Expression
|
Expressed in hippocampal neurons at protein level
|
Structure
|
Interacts with BST2, SHANK3.
|
Alternative Nomenclature
|
KIAA0672 antibody
NPC A 10 antibody
Rho GTPase activating protein RICH2 antibody
RhoGAP interacting with CIP4 homologs protein 2 antibody
|
|
|