General Information
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Product
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MAP3K4 Antibody FITC-Conjugated
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Description
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FITC-Conjugated Mitogen-activated protein kinase kinase kinase 4 Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 1558-1608 on human MAP3K4 protein.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.50 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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Immunohistochemistry |
1:50-1:100 |
Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9Y6R4
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Overview
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Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6.
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Molecular Function
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Kinase, Serine/threonine-protein kinase, Transferase
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Subcellular Location
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Cytoplasm > perinuclear region
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Expression
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Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues.
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Structure
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Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. Contains 1 protein kinase domain.
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Alternative Nomenclature
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dJ473J16.1 (mitogen-activated protein kinase kinase kinase 4) antibody
FLJ42439 antibody
KIAA0213 antibody
MAP three kinase 1 antibody
MAP/ERK kinase kinase 4 antibody
MAP3K4 antibody
MAPKKK4 antibody
MEK kinase 4 antibody
MEKK4 antibody
Mitogen-activated protein kinase kinase kinase 4 antibody
MTK1 antibody
predicted protein of HQ0412 antibody
PRO0412 antibody
RP3-473J16.4 antibody
SSK2/SSK22 MAP kinase kinase kinase, yeast, homolog of antibody
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