General Information
|
|
Product
|
Aquaporin 4 Antibody FITC-Conjugated
|
Verified Applications
|
ELISA, ICC, IF, IHC, IP, WB
|
Host
|
Rabbit
|
Species Cross Reactivity
|
Bovine, Human, Sheep, Mouse, Rat
|
Immunogen
|
Synthetic peptide taken within amino acid region 300-323 on rat Aquaporin 4 protein.
|
Accession #
|
NCBI: NP_001641
|
Physical Properties
|
|
Quantity
|
100 µg
|
Volume
|
200 µl
|
Concentration
|
0.50-0.62 µg/µl in antibody stabilization buffer
|
Immunoglobulin
|
IgG
|
Form
|
FITC-Conjugated
|
Clonality
|
Polyclonal
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
ELISA
|
1:10,000
|
Immunocytochemistry
|
1:100
|
Immunofluorescence
|
1:100
|
Immunohistochemistry
|
1:100
|
Immunoprecipitation
|
1:200
|
Western Blot
|
1:500
|
Protein
|
Uniprot #
|
P55087
|
Overview
|
Forms water specific channel. Osmoreceptor which regulates water balance and mediates water flow within CNS.
|
Molecular Function
|
Transport
|
Subcellular Location
|
Membrane; Multi-pass protein
|
Expression
|
Abundant in mature brain but only weakly detectable in eye, kidney, intestine, and lung.
|
Structure
|
Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
|
Alternative Nomenclature
|
AQP 4 antibody
Aquaporin type 4 antibody
Aquaporin-4 antibody
HMIWC2 antibody
Mercurial insensitive water channel antibody
MGC22454 antibody
MIWC antibody
WCH 4 antibody
|
|
|