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General Information
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Product
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PDE2A1 Antibody FITC-Conjugated
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Description
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FITC-Conjugated Phosphodiesterase 2A1 Antibody N-epitope
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey, Mouse, Rat
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Immunogen
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Synthetic peptide corresponding to region within amino acids 1-50 on N-terminus of human PDE2A1 protein.
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| Specificity |
This antibody will detect PDE2A1 only. |
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Accession #
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NCBI: NP_001230713.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Determinant
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N-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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| Immunohistochemistry |
1:100 |
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Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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O00408
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Overview
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Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.
Isoform PDE2A2: Regulates Mitochondrial cAMP Levels and Respiration.
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Molecular Function
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Calcium channel activity, cAMP binding, cGMP binding, cGMP-stimulated cyclic-nucleotide phosphodiesterase activity; drug binding; metal ion binding; protein homodimerization activity; TPR domain binding
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Subcellular Location
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Cytoplasm
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Expression
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Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas.
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Structure
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Belongs to the cyclic nucleotide phosphodiesterase family. PDE2 subfamily.
Contains 2 GAF domains.
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Alternative Nomenclature
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Phosphodiesterase 2A 1
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PDE2A1 Positive Control
PDE2A1 Antibody
PDE2A1 Antibody BIOTIN
