General Information
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Product
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VKORC1 Antibody
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Description
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Vitamin K epoxide reductase complex subunit 1 Antibody
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Verified Applications
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ELISA, ICC, IF, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 10-60 on human VKORC1 protein.
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Accession #
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GenBank: AJE63371.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.65-0.70 µg/µl in antibody stabilization buffer
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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Confocal Microscopy
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1:250
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DB
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1:50,000
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ELISA
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1:50,000
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Immunocytochemistry
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1:250
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Immunofluorescence
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1:250
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Immunohistochemistry
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1:250
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Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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Q6TEK4
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Overview
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Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development.
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Molecular Function
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Oxidoreductase, Quinone binding, vitamin-K-epoxide reductase
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Subcellular Location
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Endoplasmic reticulum membrane; Multi-pass membrane protein
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Expression
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Highly expressed in liver. Detected at lower levels in lung, kidney and testis.
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Alternative Nomenclature
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3-epoxide reductase subunit 1 antibody
EDTP308 antibody
FLJ00289 antibody
IMAGE3455200 antibody
MGC2694 antibody
MST134 antibody
MST576 antibody
Phylloquinone epoxide reductase antibody
Vitamin K dependent clotting factors deficiency 2 antibody
Vitamin K epoxide reductase complex subunit 1 antibody
Vitamin K1 2 antibody
Vitamin K1 epoxide reductase (warfarin sensitive) antibody
VKCFD2 antibody
VKOR antibody
VKORC1 antibody
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